International Medical Journal     Volume 30, Number 1
CONTENTS
EDITORIAL 2 Nanomedicine and Nanotechnology: A New Advanced Therapeutic Path for the Treatment, Diagnosis and Prevention of Alzheimer's Disease

Amarendra N. Singh

REVIEW ARTICLE 5

Perinatal Depression and Anxiety during the COVID-19 Pandemic: A Review and Future Direction

Chika Kubota, Toshiya Inada

10 The Effectiveness of Omecamtiv Mecarbil as an Innovative Therapy on Heart Failure Patients: A Systematic Review

Rivaldo Go, Annisa Putri Risa Swara, A. Sri Ramadani Jabir, Itzar Chaidir Islam

ORIGINAL ARTICLE 14 Does Gender and Locality Impact Dysfunctional Anxiety Caused by the Coronavirus Pandemic? A Cross-Sectional Study of the Residents of Hyderabad, Pakistan

Aimen Farogh Anjum, Zulfiqar Ali Laghari, Noman Sadiq

17 Cephalometric Variables Influencing Soft Tissue Profile Beauty in Pakistani Population

Huma Saleem, Syed Shah Faisal, Syed Sheeraz Hussain

21 Fact-Finding on the Quality of Crude Drugs in Clinical Practice (II): Ingredient Amount for Ephedra and Five Other Herbs

Koji Sakata, Masaki Baba, Hiroshi Odaguchi, Toshihiko Hanawa, Shuji Yakubo

26 Frequency of Hematologic and Solid Malignancies in the Family History of Patients with Myeloid Neoplasms (I): Ingredient Amount

Alaa Ali, Batool Yassin, Ali Almothaffar

30 Dentoalveolar and Soft Tissue Compensation in Class III Malocclusion

Aws Hashim Ali Al-Kadhim, Nur Adila Khairuzzaman, Wan Nur Hafizah AB Halim, Azrul Hafiz

33 The Possible Role of rs2227631 and rs1799889 Polymorphisms of SERPINE1 in Idiopathic Recurrent Miscarriage

Baharak Bagheri, Nastaran Asghari Moghaddam, Sina Mirzaahmadi

37 Post Dural Puncture Headache: The Different Quincke Spinal Needles in Caesarean Section Patients in Somalia

Özlem Deligöz, Zeliha Tuncel

41 Relationship between the Characteristics of Esophageal Hiatal Hernia and Mallory-Wise Syndrome in Aged Patients

Kohsaku Nitta, Toshihide Harada, Fumiko Ishizaki, Masakazu Ishizaki, Yumiko Nitta, Hiroyuki Katsuoka, Shusaku Nitta

44 Music Relaxation Therapy Effectively Reduces Fatigue in Patients Under Hemodialysis

Santi Damayanti, Siti Fadlilah, Cornelia Dede Yoshima Nekada, Susan Umbu Tanda, Ariyanto Nugroho, Eko Mindarsih

48 Relationship between the Characteristics of Goat therapy and Medical Costs

Kohsaku Nitta, Toshihide Harada, Fumiko Ishizaki, Masakazu Ishizaki, Yumiko Nitta, Hiroyuki Katsuoka, Shusaku Nitta

CASE REPORT 51 A Case of Periradicular Surgery: Apicoectomy and Obturation of the Apex

Aws Hashim Ali Al-Kadhim, Sarah Taha Yousif Al-Ani, Syatirah Najmi Abdullah, Nalisha Mohamad Ramli

54 Information for Authors