1. Title should be concise (no more than 20 words) and spelled with initial capital letter instead of all capital letters at the first page of manuscript.

2. All submissions should be accompanied by the first page of manuscript listing (1) full first names and (2) surnames (surnames must be typed in bold script to discriminate it from first name), affiliations and addresses of the authors 

3. A corresponding author's name, and e-mail address must be specified separately from the author's names at the first page of manuscript.

4. A structured abstract of no more than 200 words must be provided at the 2nd page of manuscript and contain the following (one example):

          1) Objective: An introductory sentence indicating the objective and purpose of the study.

          2) Design: A briefly worded description of the study design.

          3) Materials and Methods: Quantity and quality of Materials and a description of experimental procedures including applicable statistical evaluation.

          4) Results: A summary of the new, previously unpublished data and results.

          5) Discussions

          6) Conclusions: Statement of the study's conclusion.

Original article, Review article and Case Report require structured abstract. Abstract is not always necessary in Editorial, Letter to the editor. If you wish to include it, you may attach non-structured one.

5. 3-5 key words which must be with small letter unless special necessity as well as a short title not exceeding 50 letters must be provided. These will be printed after abstract.

6. Headline:

          1) Big headline should be written in all capital letters.

          2) Crosshead, if any, should be spelled with a capital initial.

          3) Subhead, if any, should be spelled with a capital initial and italicized.

7. Paragraph: At the beginning of the first sentence, several letters of blank space should be made.

8. Manuscripts should be double spaced, on A4 paper. These should be numbered sequentially in the lower middle place.

9. Original articles are usually up to 3,000 words and 30 references with a maximum of 4 tables and figures (total).Review articles 3,000 words long, with a maximum of 4 tables and figures (total) and no more than 60 references. Excellent review articles are especially welcome.

Short communications 1,200 words long, with a maximum of 2 tables and figures (total) and no more than 15 references. 

Case reports describe, in 750 words, an interesting case or cases that a general physician might encounter, in which there was some difficulty in reaching a diagnosis, and that provides a teaching point. Preferably the case should have a good illustration, 2 figures and 10 references.

Letters to the editor intended for publication should be a maximum of 500 words, 10 references, one table or figure, and should be sent to the editor at the address given.

10. If you have registered as a preprint, please indicate this in your paper.

11. After a final edited version of a paper has been approved by the editor, further changes should be limited to computer's errors, such as illegible letters, otherwise it may be necessary to make a charge. During proofreading by author, it is prohibited to revise minor corrections and polish up text at this final stage because author must submit the final version of text to the publisher from the beginning. That is proofreading is only to check up if original text is properly laid out or not.

12. Submission of a paper to the Journal will be held to imply that it represents an original contribution not previously published (except in the form of an abstract or preliminary report); that is not being considered for publication elsewhere; and that if accepted by the Journal it will not be published elsewhere in the same form without the consent of the Editors.

13. PDF file will be supplied to a corresponding author after the galley has been completed.